If you're searching for a natural hangover remedy that actually works, you’ve probably come across Dihydromyricetin, or DHM. This plant-based compound is quickly gaining popularity as one of the most effective ways to relieve hangover symptoms. But is DHM really the solution we’ve been waiting for?
According to a groundbreaking study from UCLA, the answer might be yes.
What Is Dihydromyricetin (DHM)?
Dihydromyricetin is a natural flavonoid found in the Hovenia dulcis tree, commonly known as the Japanese raisin tree. Traditionally used in Eastern medicine to support liver health and detoxification, DHM is now being studied for its potential as a powerful hangover remedy.
Unlike many over-the-counter hangover cures that simply mask symptoms, DHM targets the root causes of hangovers by supporting alcohol metabolism and protecting the brain from alcohol’s effects.
The Science Behind DHM as a Hangover Remedy
A study published in the Journal of Neuroscience by researchers at UCLA explored DHM’s effectiveness in reducing alcohol intoxication and withdrawal symptoms.
Study Reference:
Shen, Y. et al. (2012). Dihydromyricetin as a novel anti-alcohol intoxication medication. Journal of Neuroscience, 32(1), 390–401.
View the study
Key Findings of the Study:
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Faster Sobriety: Rats given DHM sobered up significantly faster than those given alcohol alone.
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Reduced Hangover Symptoms: DHM helped reduce anxiety, brain fog, and physical hangover effects the following day.
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Brain Protection: DHM limited alcohol’s impact on GABA-A receptors, which are responsible for the sedative effects of drinking.
These findings suggest that DHM can help prevent hangovers and support recovery after drinking.
How DHM Helps with Hangovers
Here’s how DHM for hangovers works:
✅ Supports Liver Detox
DHM helps the liver break down alcohol more efficiently, reducing the buildup of toxic byproducts like acetaldehyde.
✅ Rebalances Brain Chemistry
By regulating GABA-A receptor activity, DHM may reduce mental sluggishness, anxiety, and irritability that often follow a night of drinking.
✅ Eases Next-Day Symptoms
DHM has been shown to alleviate physical hangover symptoms such as nausea, headache, and fatigue.
How to Take DHM for Hangover Relief
DHM is available in supplement form, often as capsules, powders, or hangover patches. It’s best taken before or while drinking, although many users report benefits when taking it after drinking as well.
For optimal results, pair DHM with:
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NAC (N-acetylcysteine) to support liver detoxification
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B Vitamins to replenish nutrients depleted by alcohol
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Vitamin C to combat oxidative stress
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Electrolytes for hydration and mineral balance
This combination provides a comprehensive approach to hangover prevention and recovery.
Is DHM Safe?
DHM is considered safe when used as directed. It’s a naturally derived compound with no known major side effects. However, you should consult a healthcare professional before use, especially if you’re taking medications or have liver conditions.
Final Thoughts: Is Dihydromyricetin the Best Natural Hangover Cure?
If you’re looking for a science-backed hangover supplement, Dihydromyricetin is one of the most promising options available today. Unlike many hangover products that only treat symptoms, DHM helps your body process alcohol more effectively and may reduce both short- and long-term effects of drinking.
While the best way to avoid a hangover is still moderation, DHM offers real support for recovery when a drink turns into one too many.